Chemistry Heterocyclic Building Blocks Thiophenes 4-Phenyl-6H-Thieno[3,2-F][1,2,4]Triazolo[4,3-A][1,4]Diazepine

4-Phenyl-6H-Thieno[3,2-F][1,2,4]Triazolo[4,3-A][1,4]Diazepine

Arylation: The phenyl ring in 4-phenyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine contains a reactive benzene ring, which can undergo various arylation reactions. For example, it can undergo electrophilic aromatic substitution reactions with various electrophiles, such as halogens (e.g., bromination or chlorination) or Friedel-Crafts acylation. Nucleophilic Substitution: The compound contains several nitrogen and sulfur atoms, which can participate in nucleophilic substitution reactions with appropriate electrophiles. For instance, you can react it with alkyl halides to form N-alkylated or S-alkylated derivatives. Reduction: The compound may be reduced by reducing agents like lithium aluminum hydride (LiAlH4) or sodium borohydride (NaBH4) to yield corresponding reduced products. Oxidation: It can undergo oxidation reactions using various oxidizing agents to produce oxidized derivatives. Ring Opening: The compound's fused ring system contains several potential sites for ring-opening reactions under appropriate conditions. Cyclization: Depending on the reaction conditions and reactants, it might participate in cyclization reactions to form other cyclic compounds. Substitution Reactions: Depending on the specific functional groups present, it can undergo substitution reactions with appropriate nucleophiles or electrophiles. Hydrogenation: If there are unsaturated bonds present in the molecule, it can potentially undergo hydrogenation reactions using hydrogen gas and a suitable catalyst.

Further Reading:

Framework+−

(9H-Fluoren-9-Yl)Methyl (2-(Thiophen-2-Yl)Ethyl)Carbamate 1-(Thiophen-2-Yl)Ethan-1-One 2,2'-Bithiophene 2,2':5',2''-Terthiophene 2,3-Dihydrothieno[3,4-B][1,4]Dioxine 2,5-Dibromothiophene 2,5-Diphenylthiophene 2-(Thiophen-2-Yl)Pyridine 2-(Trifluoromethyl)Thiophene 2-Chlorothiophene 2-Ethynylthiophene 2-Iodothiophene 2-Methoxythiophene 2-Nitrothiophene 3-Bromothiophene 3-Chlorothiophene 3-Fluorothiophene 3-Methoxythiophene 3-Methylthiophene 3-Nitrothiophene 3-Phenylthiophene 4,4,5,5-Tetramethyl-2-(Thiophen-2-Yl)-1,3,2-Dioxaborolane 4,4,5,5-Tetramethyl-2-(Thiophen-3-Yl)-1,3,2-Dioxaborolane 4,5,6,7-Tetrahydrothieno[2,3-C]Pyridine 4,5,6,7-Tetrahydrothieno[3,2-C]Pyridine 4,7-Di(Thiophen-2-Yl)Benzo[C][1,2,5]Thiadiazole 4,8-Di(Thiophen-2-Yl)Benzo[1,2-B:4,5-B']Dithiophene 4-Phenyl-6H-Thieno[3,2-F][1,2,4]Triazolo[4,3-A][1,4]Diazepine 4H-Cyclopenta[2,1-B:3,4-B']Dithiophene 4H-Thieno[3,2-B]Pyrrole 4H-Thieno[3,4-C]Pyrrole-4,6(5H)-Dione 5,6-Dihydro-4H-Cyclopenta[B]Thiophene 5-(Thiophen-2-Yl)Isoxazole 5-Benzyl-4,5,6,7-Tetrahydrothieno[3,2-C]Pyridine 5-Phenylthiophen-2-Amine Benzo[1,2-B:4,5-B']Dithiophene Dibenzo[B,D]Thiophene Dihydrothiophen-3(2H)-One Dithieno[3,2-B:2',3'-D]Thiophene Ethyl Thiophene-2-Carboxylate Ethyl Thiophene-3-Carboxylate Methyl Thiophene-3-Carboxylate N,N-Diphenyl-4-(Thiophen-2-Yl)Aniline Phenyl(Thiophen-2-Yl)Methanone Thieno[2,3-B]Pyridine Thieno[2,3-C]Pyridine Thieno[2,3-D]Pyrimidine Thieno[3,2-B]Pyridine Thieno[3,2-B]Thiophene Thieno[3,2-C]Pyridine Thieno[3,2-D]Pyrimidine Thieno[3,4-B]Thiophene Thiophen-2-Ylboronic Acid Thiophen-2-Ylmethanol Thiophen-3-Amine Thiophen-3-Ol Thiophene-2-Carbaldehyde Thiophene-2-Carbonitrile Thiophene-3-Carbaldehyde Thiophene-3-Carbonitrile Thiophene-3-Carboxamide Thiophene-3-Carboxylic Acid

By Key Group+−

Acetylthiophene Aminothiophene Bromothieno Chlorothieno Chlorothiophene Cyanothiophene Dibromothieno Dibromothiophene Dichlorothieno Dichlorothiophene Dihydrothieno Dihydrothiophene Dihydroxythiophene Dimethylthieno Dimethylthiophene Dithiophene Fluorothiophene Formylthiophene Hydroxythiophene Iodothieno Iodothiophene Methylthieno Nitrothiophene Oxotetrahydrothiophene Terthiophene Tetrahydrothieno Thiophen-Amine-Hydrochloride Thiophenecarboxaldehyde Thiphen-Amine-Hydrochloride Trithiophene

By Route Intermediates+−

cLogP+−

H-Acceptors+−

H-Donors+−

Polar Surface Area+−

Druglikeness+−

NNCH/NNH+−

sp3-Atoms+−

Non-Aromatic Rings+−

Aromatic Rings+−

Rotatable Bonds+−

Typically In Stock
Purity
  • Please Select
  • 99+%
  • 99%
  • 98+%
  • 98%
  • 97+%
  • 97%
  • 96+%
  • 96%
  • 95+%
  • 95%
  • 93%
  • 90+%
  • 90%
Size
  • Please Select
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • 10g
  • 25g
  • 100g
  • 500g
  • 1000g
  • 1kg
Clear Filters
(+)-JQ1

click to sign in and save

A5298421268524-70-498%

(+)-JQ1

$130.00/250mg

Detail
JQ-1 (carboxylic acid)

click to sign in and save

A717701202592-23-298%

JQ-1 (carboxylic acid)

$357.00/1g

Detail
CPI-203

click to sign in and save

A6392141446144-04-298+%

CPI-203

$21.00/1mg

Detail
(R)-(-)-JQ1 Enantiomer

click to sign in and save

A1187711268524-71-598%

(R)-(-)-JQ1 Enantiomer

$18.00/2mg

Detail
2-((6R)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetic acid

click to sign in and save

A640482202592-24-398%

2-((6R)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetic acid

$234.00/100mg

Detail
1    page 1 of 1 Pages

Inquiry